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These antiapoptotic mechanisms constitute vulnerabilities and, consequently, targeting them with either BCL2 family inhibitors 24,25,34 or via suppression of cFLIP 26 kills senescent cells

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Among them, MgI injection demonstrated the highest overall response rate and the most significant improvement in aspartate aminotransferase (AST), whereas CG injection was most effective in reducing ALT levels (van Rossum et al., 2001

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