Keep in mind that these downstream effects are based on deduction, so theyre largely hypothetical
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46 APAP can freely cross the selective maternal-fetal barrier of the placenta, after which it can then be metabolized by fetal hepatocytes, causing fetal hepatic necrosis if appropriate therapy with NAC is not administered in a timely manner
Estrogen-driven PDGF production has a significant effect on angiogenesis, with estrogen demonstrated to be proangiogenic both in vitro and in vivo [188]
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