[2] Antioxidant enzymes, such as glutathione peroxidases and peroxiredoxins, generate glutathione disulfide during the reduction of peroxides such as hydrogen peroxide (H 2 O 2 ) and organic hydroperoxides (ROOH): [3] 2 GSH + ROOH GSSG + ROH + H 2 O Other enzymes, such as glutaredoxins, generate glutathione disulfide through thiol-disulfide exchange with protein disulfide bonds or other low molecular mass compounds, such as coenzyme A disulfide or dehydroascorbic acid
Chronic exposure to toxins may deplete glutathione levels
In addition, three important antioxidant enzymes, GST, SOD, and ascorbate peroxidase (APX), displayed significantly higher activities in transgenic lines after inoculation with F
10.1186/s13287-018-1067-y 105 MahdipourE.SalmasiZ.SabetiN
Description Glutathione is a naturally occurring compound in the body