By overriding the normal system used by the brain to coordinate its many activities, nicotine alters the pattern of release into gaps between nerve cells of many neurotransmitters, including acetylcholine, dopamine, serotonin and many others
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Beyond its addictive properties, short-term or long-term exposure to nicotine in adults has not been established as dangerous "Electronic Cigarettes: Vulnerability of Youth"
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Some researchers suggest that the degree of carcinogenicity of these radioactive elements is sufficient to account for most, if not all, cases of lung cancer related to smoking