Improving the folding/aggregation changes observed with mutant ATXN3 has been successful with compounds such as 17-DMAG (an Hsp90 inhibitor and autophagy inducer), temsirolimus (a rapamycin analog that increases autophagy), cordycepin (autophagy inducer), and H1152 (a ROCK inhibitor shown to decrease levels of mutant ATXN3) [84, 90, 92, 172]
2018 (review): 11 trials in 251 athletes (14 g/day up to 6 months) and 17 studies in 237 recreationally active adults showed mixed results
It's the molecule your mitochondria pass electrons through to make ATP (your cellular energy currency), and the molecule your sirtuins and PARP enzymes burn through when they do DNA repair
NAC : Has unique neuroprotective effects by regulating glutamate, the brains main excitatory neurotransmitter
If you are still evaluating outcomes and expectations, you may find it helpful to read Does IV vitamin therapy really work