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What makes BPC-157 particularly interesting for skin healing applications is its remarkable stability

Because so much of GHK-Cus activity is copper-mediated, it is difficult in some experiments to separate specific tripeptide signaling from generic copper effects a point made concrete by the finding that the MMP-2 effect was reproduced by copper ions alone while the collagen-synthesis effect required the intact peptide

This ability gives it a broader influence on cellular function, especially in areas such as the nervous system, the liver, and the brain

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The T9 and T11 vertebral plates of the rats were subsequently clamped, and the rats were placed on a spinal cord percussion device (Precision Systems and Instrumentation IH Spinal Cord Percussion Device, USA) with the percussion force set to 250 kdynes, resulting in a moderate SCI model