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the present invention thus also provides compositions which comprise the HGF analogs/mimics as described herein, usually together with a pharmacologically suitable carrier or diluent

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This recruitment is crucial for efficient mitophagy: depleting all three VDACs impairs Parkins targeting to defective mitochondria and mitochondrial degradation, yet each individual VDAC can redundantly support Parkin recruitment and mitophagy (147)

608 Upon entry into the host cell, it may cause cytokine storms and immune dysregulation, disrupt the BBB, and reduce A clearance, ultimately resulting in neuroinflammation and A aggregation