It depends on the vendor
Moisture can reduce peptide stability
See a doctor if you have high B12 and High B12 on a blood test doesnt always require action, but certain combinations warrant prompt evaluation: B12 above 1,000 pg/mL without supplementation or injections Unexplained fatigue, weight loss, abdominal pain, or night sweats alongside elevated B12 Abnormal liver function tests (ALT, AST, bilirubin) or kidney markers (creatinine, GFR) on the same panel Abnormal complete blood count (CBC), especially elevated white blood cells, red blood cells, or platelets B12 levels that are rising over serial measurements without a clear dietary or supplement explanation What to do about high B12 levels There is no specific treatment for high vitamin B12 because the B12 level itself is almost never the problem
Adhering to them isn't about being overly cautious
Just look at the history of people with ME (myalgic encephalomyelitis) or with Long-Covid, and how they have been ill-diagnosed and not well treated, and you realize how mediocre the specific evaluation of many people with unexplained symptoms may have been